Trimix Injection Therapy
Trimix is a physician-prescribed, compounded medication injected at the base of the penis that may help men achieve an erection when ED pills are not effective or cannot be used. It is used off-label and is not FDA-approved as a combination product.
An option when pills fall short
Trimix combines three medications that relax blood vessels and may increase blood flow to the penis. Unlike oral medications, which must travel through the digestive system, Trimix acts locally, and some men who have not responded to pills find it helpful.
Self-injection can feel intimidating, so we teach you the technique in the office, supervised, before you ever use it at home. Your provider typically starts with a conservative dose and adjusts it carefully.
Because Trimix is a prescription medication, it begins with a medical evaluation. We review your heart health, other medications and history, and we set clear guidance on timing, dosing and safety.
At a glance
- Visit
- Initial training visit in office, then follow-ups
- Onset
- Varies; your provider will explain what to expect
- Dosing
- Individually adjusted by your provider
- Prescription
- Compounded medication prepared by a pharmacy
Who it may help
Men who have tried other options and notice:
- Little or no response to ED pills
- Side effects from oral medication
- Erectile difficulty after prostate treatment
- Erectile problems related to diabetes
- Medications that prevent pill use
- A wish for an on-demand option
What to expect
- 1Medical evaluation. We review your health, medications and goals to be sure Trimix is safe and appropriate.
- 2Supervised first dose. Your provider teaches the technique and administers a test dose in the office to find a starting amount.
- 3Ongoing guidance. We refine your dose at follow-up visits and review safe use and storage. If an erection lasts longer than 4 hours, go to the nearest emergency room or dial 911 right away. Do not wait for a text reply.
Guided by a physician-led team
Dr. Deborah Viglione, MD, and our nurse practitioners prescribe and monitor Trimix as part of broader care for your health. Our goal is to make the process clear and comfortable, with room for every question you may have.
Trimix questions
Does the injection hurt?
The needle is very fine, and many men report only a brief pinch. We practice the technique with you in the office first.
What are the possible side effects?
Possible effects include a mild ache, bruising or an erection that lasts longer than intended. An erection lasting more than 4 hours (priapism) is a medical emergency: go to the nearest emergency room or dial 911 immediately. Our office is text and voicemail only, so do not rely on a text message in this situation. We give you a written safety plan at your first visit.
How often can I use Trimix?
Use is typically limited to a certain number of times per week, and your provider will set a schedule that is safe for you.
Is Trimix FDA-approved?
Trimix is a compounded medication and is not FDA-approved as a combination product. Its component medications are used off-label for this purpose, and we explain the details at consultation.
Visit us in Gulf Breeze
103 Nightingale Ln, Gulf Breeze, FL 32561 · Get directions
Text or leave a voicemail at (850) 934-8138. Serving Gulf Breeze, Pensacola, Pensacola Beach and Navarre.
Related: GAINSWave · P-Shot (Priapus Shot) · Emsella Pelvic Floor Treatment
Individual results vary. This page is for information only and is not medical advice. Compounded medications are not FDA-approved, and Trimix is an off-label use. It requires a prescription and a medical evaluation. An erection lasting more than 4 hours is an emergency: go to the ER or dial 911.